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News

2019

DateDescription
NOV 22UCI-led study reveals how consuming alcohol affects the circadian rhythm of the liver leading to disease; Targeting the liver's circadian rhythm may lead to new treatments for alcoholic liver disease
JUL 24The genome of Peromyscus leucopus, natural host for Lyme disease and other emerging infections
JUL 24Mouse, not just tick: New genome heralds change in Lyme disease fight; UCI-led study points toward new ways to prevent disease transmission
JUL 21What’s the best time of day to exercise, morning or evening?
FEB 25Dr. McClelland's group published a study in Journal of Experimental Medicine describing the discovery of a new trehalose phospholipid in Salmonella that has functional convergence with a phospholipid in Mycobacteria.
JAN 14Dr. McClelland's group published a study in Nature Communications describing antibacterial compounds selective for intracellular Salmonella Typhimurium

2018

DateDescription
OCT 26Dr. McClelland's group published a study in PLoS Pathogens describing the role of glucose metabolism in the adaptation of intracellular Salmonella to the reactive nitrogen species synthesized in the innate host response
JAN 11Dr. Yongsheng Shi's group published a study in Cell describing the discovery of a roadblock gene that prevents somatic reprogramming.

2017

DateDescription
DEC 21UC Irvine anatomy and neurobiology professor Daniele Piomelli advocates ending a federal block on marijuana research to understand its real benefits and risks.
DEC Department of Microbiology & Molecular Genetics chair Rozanne M. Sandri-Goldin and professor Emiliana Borrelli are named Chancellor's Professors.
NOV 16UC Irvine molecular and cellular neurobiologist Emiliana Borrelli, PhD, received the prestigious 2017 Camillo Golgi Medal at the University of Brescia in Italy.
NOV 16Amid concerns about CRISPR gene-editing tools, UC Irvine vector biologist Anthony James says his lab equips test mosquitos with self-limiting gene drives.
OCT 17Faculty member Emiliana Borrelli, PhD, has been named a Knight of the National Order of the Légion d’Honneur for reinforcing France's scientific partnerships with the U.S. Congratulations!
OCT 05Congratulations to our faculty members Klemens Hertel, PhD, and Bert Semler, PhD, for winning the 2017 UC Irvine School of Medicine Graduate Teaching Award!
SEP 15Drs. Sandri-Goldin and Borrelli have been appointed Chancellor’s Professors, a distinction given to UCI faculty members who have demonstrated unusual academic merit. Congratulations!
AUG 10A UC Irvine-led study shows that a low-calorie diet helps keep energy-regulating processes humming and the body younger.
JULY 11Yongsheng Shi, Phd, has received seeding funding from UC Irvine Office of Research for a Center for RNA Biology and Therapeutics!
MAY 08UC Irvine molecular biologist Anthony James to lead a $2-million initiative to combat malaria in Africa.

2016

DateDescription
NOV 07UC Irvine-MIT team forge new approach against Salmonella and other pathogens, an immunization strategy could prevent gastrointestinal disease.
NOV 03UC Irvine researcher Manuela Raffatellu and colleagues show that proteins produced by beneficial gut microbes can block inflammation-causing salmonella and E. coli.
JUL 06Microbiology and Molecular Genetics Professor Emiliana Borrelli, PhD, and her colleagues have discovered the key cellular mechanism that underlies antipsychotic-induced parkinsonism.

2015

DateDescription
DEC 21UC Irvine’s Anthony James honored as one of Orange County’s most influential by the Orange County Register.
DEC A study by Anthony James, PhD, in Proceedings of the National Academy of Sciences titled "Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi" has received wide attention, including on NIH Director Francis Collins' blog.
NOV 17Anthony James, professor of microbiology and molecular genetics, collaborates on efforts to edit a mosquito genome to prevent spread of malaria.
JUL 15UC Irvine infectious disease expert Dr. Alan Barbour tells NBC News that climate change and other factors have led to the spread of Lyme disease.
JUN 08Alan Barbour, MD, an expert on tick-borne diseases helps us understand lyme disease in his recent interview with WNYC 93.9 FM.
APR Vladimir Diaz-Ochoa, a graduate student from Dr. Manuela Raffatellu's lab, has been selected as the 2015 Graduate Hooding Ceremony student speaker. Congratulations!
MAR 29Postdoctoral researcher Brett Hanson wins the Jane E. Raulston Award for best poster presentation by a postdoc from the Chlamydia Basic Research Society.
FEB 19Anthony James, UC Irvine professor of microbiology and molecular genetics, comments on the mosquito gene trial in the Florida Keys.

2014

DateDescription
NOV 01A team led by Yongsheng Shi, PhD, published a study in the journal Genes & Development that gives new insights into the mechanism for mRNA 3' processing.
OCT 02Bert Semler, PhD, discusses enterovirus D68 with the Dallas Morning News.
SEP 30A new study from Dr. Michael Demetriou’s group uncovers important process for immune system development:
JUN A great week for the Raffatellu lab at the American Society for Microbiology General Meeting in Boston. Dr. Judith Behnsen was invited to give an oral presentation, Martina Sassone-Corsi was selected to receive a travel award, and Vladimir Diaz-Ochoa was selected to receive the Richard and Mary Finkelstein travel award.
MAY 14UC Irvine School of Medicine researchers identify link between colon cancer and metabolism.
MAY A study from Dr. Yongsheng Shi's lab on the role of mRNA alternative polyadenylation on stem cell self-renewal is featured on the cover of the April 16 issue of EMBO Journal.
APR Brett Hanson in the Tan Lab has been selected for an NIH F32 National Research Service Award (2014-2016)
APR Dr. Sid Golub, professor emerius of our department, has been appointed as the Interim Director of the Sue & Bill Gross Stem Cell Research Center, effective September 1, 2013
APR Manuela Raffatellu has been selected as a Kavli Frontiers Fellow of the National Academy of Sciences. The Academy's Kavli Frontiers of Science symposia bring together outstanding young scientists to discuss exciting advances and opportunities in a broad range of disciplines.
APR Stefan Jellbauer (Raffatellu lab) received a travel award to present his research on neutrophils at the Southern California Flow Symposium.
MAR 14An experimental drug may help people with treatment-resistant leukemia and lymphoma without traditional chemotherapy, a UC Irvine study shows.
MAR 14UC Irvine researcher David Fruman discusses a new drug that shows promise in treating chronic leukemia and lymphoma in the New England Journal of Medicine.
MAR 11UC Irvine researchers find new stem cell self-renewal mechanism.
FEB 06UC Irvine study by Manuela Raffatellu, MD, reveals how immune protein allows salmonella to grow and cause food poisoning.
JAN 30UC Irvine researcher Marian Waterman is among those awarded a $540,000 CIRM grant in connection with a new kind of microscopy to identify stem cell populations.
JAN This year's recipient of the Harris S. Moyed Graduate Fellowship award for the Department of Microbiology and Molecular Genetics is Haik Mkhikian from Dr. Michael Demetriou's lab.

2013

DateDescription
NOV Michael McClelland has been awarded a grant from the United States Department of Agricultureentitled “Molecular mechanisms underlying Salmonella attachment to fruits and nuts”, in a collaboration with Wei Zhang at the Illinois Institute of Technology.
NOV Michael McClelland published a paper in Infection and Immunity entitled “Novel Determinants of Intestinal Colonization of Salmonella enterica Serotype Typhimurium Identified in Bovine Enteric Infection.”
OCT Dr. Marian Waterman has been invited to be a part of Faculty of 1000 (Developmental Molecular Mechanisms)
OCT Michael McClelland presented a talk and six posters at the ASM Conference on Salmonella: The Bacterium, the Host and the Environment
OCT Michael McClelland and Dan Mercola were awarded a grant from the DOD CDMRP entitled “Validation of Biomarkers of the Tumor Microenvironment”.
SEP Michael McClelland published a paper in BMC Genomics entitled “Use of a promiscuous, constitutively-active bacterial enhancer-binding protein to define the sigma54 (RpoN) regulon of Salmonella Typhimurium LT2.”
SEP Michael McClelland published a paper in BMC Genomics entitled “Probing the ArcA regulon under aerobic/ROS conditions in Salmonella enterica serovar Typhimurium.”
SEP 01Dr. Sidney Golub was appointed Interim Director of the Sue & Bill Gross Stem Cell Research Center at UCI as of Sept. 1, 2013.
SEP Suzi Klaus, an MSTP student in the Raffatellu lab, was selected as an ARCS Scholar. This award is one of UCI's most distinguished and the scholars are selected on the basis of their academic accomplishments and promise as well as their leadership qualities.
SEP Araceli Perez-Lopez, a postdoctoral fellow in the Raffatellu lab, has been awarded a UC MEXUS-CONACYT Postdoctoral Fellowship
SEP Addgene interviews Dr. Marian Waterman on "crowd-sourced science"
AUG Michael McClelland published a paper in Molecular Microbiology entitled “The EAL domain containing protein STM2215 (rtn) is needed during Salmonella infection and has cyclic di-GMP phosphodiesterase activity.”
AUG Michael McClelland published a paper in Current Cancer Drug Targets entitled “Natural products and transforming growth factor-beta (TGF-β) signaling in cancer development and progression.”
AUG Dr. Sidney H. Golub has been appointed the Interim Director of the Sue and Bill Gross Stem Cell Research Center, effective September 1, 2013. Congratulations to Sid!
AUG Dr. Suzanne Sandmeyer, Professor of Biological Chemistry and a joint faculty appointee in the Department of Microbiology and Molecular Genetics, was recently appointed as the Grace Beekhuis Bell Chair in the Department of Biological Chemistry. Dr. Grace Bell was the first graduate to earn an MD from the UCI School of Medicine (then called the California College of Medicine) and was its first Dean.
JUL Work in the Raffatellu lab shows that a probiotic bacterium reduces the severity of Salmonella infection by hoarding iron. This work was published in the July 2013 issue of Cell Host and Microbe and selected for the cover image.
JUL Dr. Michael McClelland has been awarded a grant from the Binational Agricultural Research & Development Fund Entitled “Investigation of a new mechanism of desiccation-stress tolerance in Salmonella”, in a collaboration with Shlomo Sela at the Volcani Institute of Agricultural Research.
JUL Michael McClelland has recently published a paper in Infection and Immunity: “Mapping and Regulation of Genes within Salmonella Pathogenicity Island 12 That Contribute to In Vivo Fitness of Salmonella enterica Serovar Typhimurium.”
JUL 31Breath analysis reliably indicates presence, level of infection, UCI study finds
JUL 18Treat an upset tummy with curd: Probiotic bacterium lessens severity of salmonella infections by hoarding iron
JUN Michael McClelland has recently published a paper in Molecular Microbiology: “The intestinal fatty acid propionate inhibits Salmonella invasion through the post-translational control of HilD.”
JUN The Manuela Raffatellu and Paolo Sassone-Corsi labs report that circadian rhythms control the body's response to intestinal bacterial infections.
JUN The Center for Produce Safety awarded a grant to Michael McClelland, PhD, to study avirulent salmonella behavior in water, in composts and in vegetables.
JUN Prerak Desai, PhD, presented "The taxonomic structure of Salmonella enterica subspecies enterica" poster at the American Society of Microbiology meeting in May.
JUN Dr. Marian Waterman's lab has recently published a paper in EMBO Reports describing a new protein named RNF14 that functions in Wnt Signaling. A "Hot Off the Press" review was written about this study:
JUN 01Circadian rhythms control the body’s response to intestinal infections, UC Irvine-led study finds; the results suggest a new approach to treating pathogens such as salmonella.
MAY Michael McClelland has recently published a paper in mBio: “Evolutionary Genomics of Salmonella enterica Subspecies”
MAY Michael McClelland has recently published a paper in Cell Host & Microbe “L-asparaginase II produced by Salmonella typhimurium inhibits T cell responses and mediates virulence.”
MAR Sonia Maciejewski, a graduate student in Dr. Bert Semler's lab, has recently been awarded a Graduate Research Fellowship by the National Science Foundation. She was selected for her "outstanding abilities and accomplishments, as well as potential to contribute to strengthening the vitality of the US science and engineering enterprise". Congratulations to Sonia and Bert!
MAR Dr. Bert Semler has just been selected as an ASM Distinguished Lecturer. The American Society for Microbiology Distinguished Lecturer (ASMDL) Program (formerly known as the ASM Branch Lectureships or Waksman Foundation for Microbiology Lectures) annually selects a scientifically diverse group of distinguished lecturers to deliver lectures at ASM Branch meetings throughout the country. Lecturers are chosen through a competitive nomination process, and only the most distinguished lecturers and researchers are chosen to participate in the program.
FEB Microbe World Podcast - TWiP 51: Modifying mosquitoes with Anthony A. James
FEB 19There are different types of malaria and they're host-specific, UC Irvine professor Anthony A. James, PhD, tells the New York Times in a story about anti-malarial mosquito research.
FEB UCI microbiologist Bert Semler seeks to stop certain viruses from replicating, changing the way we fight the common cold and other illnesses

2012

DateDescription
NOV 29Rozanne Sandri-Goldin, chair of microbiology & molecular genetics, is one of 13 from UC Irvine named fellows by the American Association for the Advancement of Science.
NOV Hertel laboratory graduate student Angela Garibaldi receives a Ruth L. Kirschstein research fellowship to study the link between alternative pre-mRNA splicing and cancer.
OCT 29A team led by Yongsheng Shi, PhD, has identified the core mRNA 3' processing factor CstF64 as a critical global regulator of mRNA alternative polyadenylation.
NOV New Chlamydia Book - Ming Tan is the editor of Intracellular Pathogens I: Chlamydiales, which was just published by ASM Press.
AUG 22Dr. Bert Semler's group has identified the elusive VPg unlinkase for picornavirus infection in a recent paper published in the Proceedings of the National Academy of Sciences USA.
AUG The work of Dr. Anthony James on malaria-proof mosquitoes was featured on CBS News.
AUG Janet Liu, a graduate student in the Raffatellu laboratory, has been awarded a predoctoral research fellowship from the American Heart Association.
JUL 1Dr. Rozanne Sandri-Goldin has begun a five-year term on July 1 as Editor-in-Chief of the Journal of Virology, the premier journal for virology research.
JUN 20Dr. Emiliana Borrelli has been nominated as a contributing member of 'Faculty of 1000' Cell Signalling Section
JUN 15Dr. Alan Goldin,M.D./Ph.D. has been appointed Senior Associate Dean for Academic Affairs at UC Irvine School of Medicine.
JUN 14Vladimir Diaz-Ochoa from the Raffatellu lab is the recipient of a DECADE Student Travel Award for the ASM meeting.
JUN 10Dr. Klemens Hertel, Ph.D. has been appointed Associate Dean for Graduate Studies at UC Irvine School of Medicine.
JUN 1Dr. Marian Waterman has been selected the 2012 Research Associates Athalie Clarke Achievement Award recipient.
MAY 15Alison Isaacs from the James lab was a first author on a paper that appeared in PNAS
APR Dr. Yongsheng Shi was awarded a Research Scholar Grant from the American Cancer Society to study “Global regulation of mRNA alternative polyadenylation by oncogenes"
MAR 14UCI-led study uncovers how salmonella avoids the body’s immune response
JAN Anthony A. James was elected a 2011 Fellow of the Entomological Society of America (ESA). The designation of ESA Fellow recognizes individuals who have made outstanding contributions to entomology. He was honored for the creation of pioneering approaches to the application of research data and products to create new paradigms for arthropod management that are considered highly progressive in the area of their use.

2011

DateDescription
OCT 31New York Times: UC Irvine's Anthony James has developed a genetic modification that makes female mosquitoes unable to fly, bite people or mate.
Oct This year's recipient of the Harris S. Moyed Graduate Fellowship award for the Department of Microbiology and Molecular Genetics is Rani Najdi, from Dr. Waterman's lab
Sep Vladimir Diaz-Ochoa, a third year graduate student in the Raffatellu lab, received a travel scholarship to attend the 2011 SACNAS National Conference in San Jose, California
Aug Professor Bert Semler has been elected president of the American Society for Virology, an international organization of research scientists studying viruses that infect humans, animals, insects, plants, fungi, or bacteria.
MAY 31Work in Dr. Michael Demetriou’s laboratory establishes a link between the environment and genetics in triggering Multiple Sclerosis.
MAY 27Angela Garibaldi, a first year graduate student in the Hertel lab, received a Faculty Mentor Program Fellowship – Honorable Mention award to support her graduate work.
MAY 26Dr. Marian Waterman has been awarded this year’s Associated Graduate Studies Outstanding Faculty Mentor Award in recognition of her excellence in advising graduate students on their thesis projects and dissertation.
MAY 25Rani Najdi, a graduate student in the Waterman lab, received a prize for one of the best talks presented at the Translational Research in Cancer Genomic Medicine Training Grant meeting in Santa Ana.
MAY 10Dr. Manuela Raffatellu received the 2011 Chancellor’s Award for Excellence in Fostering Undergraduate Research in recognition of her outstanding work in mentoring undergraduate students.
MAY 08Dr. Judith Behnsen, a fellow in the Raffatellu laboratory, has been awarded a postdoctoral research fellowship from the American Heart Association.
APR 25Alison Isaacs’ PLoS Pathogen paper recently published from Dr. James’ laboratory was highlighted on World Malaria Day.
APR  12Dr. Ming Tan has been elected president of the Chlamydia Basic Research Society, an international organization for scientists studying the pathogenic bacterium, Chlamydia.
MAR 01Dr. Xiaochen Tian, a fellow in the UC Irvine lab of Dr. Rozanne Sandri-Goldin, has been awarded a postdoctoral research fellowship from the Hewitt Foundation for Medical Research.
MAR Dr. Ming Tan is the co-organizer of CBRS 2011, the fifth biennial meeting of the Chlamydia Basic Research Society.
JAN 19UC Irvine professor Bert Semler has been elected a fellow of the American Association for the Advancement of Science, the world’s largest general scientific society.

2010

DateDescription
DEC Dr. Bert Semler has been named Director of the Center for Virus Research at UC Irvine.
OCT Janet Rozovics, a fellow in the UC Irvine lab of Dr. Bert Semler, has been awarded a postdoctoral research fellowship from the Hewitt Foundation for Medical Research to support her work on human rhinovirus-host cell interactions.
SEP Professor emeritus Sidney Golub will head the Clinical Research Ethics unit of the UC Irvine Institute for Clinical and Translational Sciences.